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http://www.good-sa.com.tw/femmy/

http://www.shining-asia.com.tw/

 
 

 

艾地苯.Idebenone

 

 

 

 

 

 

  

一、Introduction:

Idebenone

Medicine product name: The Ai ground benzene

English:IDEBENONE TABLETS

[Nickname]:The Ya companion, the Qian J AN oxygen Tong, Avan 

Molecular formula:C19H30O5

Molecular weight:338.44

[Sex form]:

 

The orange goes to an orange crystallize, the crystallinity powder or piece form thing, have no smelly;BE dissolved in chloroform, methyl alcohol easiest

Or have no water ethanol, is dissolved in the acetic acid B ester easily, difficult dissolve in B alkane, is dissolved in a water scarcely .

 

[The function and use]:

Participate the cell line grain a body metabolism, organize function to have a protection to make to the energy metabolism and brain that lacks the blood Qi

Use;Can improve the metabolism that nerve inside the brain passes quality, raise the glucose utilization of the brain, promote a brain

The ATP is born, repressing lactic acid born lead oxygenation with fat, protect the stability of the afferent wall cell membrane

Sex.

Being applicable to the improvement brain blocks the linger effect, apoplexy linger effect, brain moves the brain cirrhosis etc. accompanies with of the motion is low to fall, emotion obstacle, language barrier.

 

[Special note]

Pregnant woman, breast feed to expect women to use carefully

Sometimes can appear following condition of illness:

1.allergic sex skin Zhen.

2.have a poor appetite, the stomach is painful, disgusting, diarrhea.

3.the spirit nerve respond, if move much, spasm.

4.the red cell, white cell reduce.

5.the liver SGOT, SGPT, the ALP increases high.

6.the kidney BUN increase high.

7.have no power, languid, total cholesterol and glycerin three esters increase high.

 

二、The Ai ground the medical treatment of the benzene is applied:

Was in 1986 at the earliest stage, by Japanese top pharmaceutical factory develop, afterwards the German medical treatment research team found the Ai ground benzene Idebenone and can prevent the cell was damaged, deteriorating sex disease treatment in the nerve particularly up, as A the sea Mo surname etc. disease up own obvious effect.

Through data of the collections know, currently by many know Idebenone in the data is a kind of to use to cure related disease with the brain of a kind of medicine, also by know in many cultural heritage reports, it resists oxygenation very effectively, due to it of the structure types and CoQ10 are very alike, think is belong to CoQ10 of a kind of, currently most Idebenones all of academic sex data is do treatment brain related disease of part is aging or improve the crease aspect to the skin anti- still in the research. 

 

Pharmacology poisonous reason:

Metabolize for the brain, the spirit condition of illness improvement medicine, can start the brain line grain the body breath activity, improve a cerebral ischemia of the brain energy metabolism, the improvement glucose utilization inside the brain, make the ATP creation inside the brain increase, repress the brain line grain a body born lead oxidize a fat, repress the brain line grain the body film fat over the oxygenation with the result that of film obstacle.This article the poisonous pair respond low, LD small rat, big rat, the big rat Take orally half year, the dog took orally and don't see an obvious toxicity respond for a year, have no with the result that Ji, cancer-causing, with the result that mutate a function.

 

The medicine generation dynamics:

Take orally this article  after the linger effect sufferer's rice in 6 brain Zus according to the data report, Tmax is  hours, Cmax for , remove a half- life for  hours, didn't check the original shape medicine in the urine, all in order to metabolize a thing, urine in  hours is  in the excretion rate.

 

Adaption:

The brain function that chronic and cerebral disease and the brain external injury etc. cause injures.Can improve subjective condition of illness, language, worry anxiously, suppress Yu and remember a decrease, intelligence to descend etc. spirit behavior obstacle.

 

Bad reaction:

The bad reaction occurrence rate  is or so, mainly having an allergy, skin Zhen, disgusting, have a poor appetite, diarrhea, excitement, suffer from insomnia, dizzy etc..See the white cell decrease, the liver function damage accidentally.

 

Taboo disease:

The special note takes over a long period of time, notice to check GOT, GPT etc. liver function.

 

三、The Ai ground the chemistry type of the benzene

 

Name

 

Synonyms

 

Chinese Names

 

 

Molecular Structure

 

 

Molecular Formula

 

C19H30O5

Molecular Weight

 

338.44

CAS Registry Number

 

58186-27-9

 

 

     

   

 

 

四、The Ai ground the hairdressing effect of the benzene:

The Ai ground the benzene Idebenone belong to a type of nerve protection benzene , From can repress the human body free radicals to assist enzyme Q10 living creature to synthesize a conversion since then of, is a kind of bright and orange powder.

The Ai ground the benzene was in 1986 at the earliest stage, by Japanese top pharmaceutical factory develop, afterwards the German medical treatment research team found, the Ai ground the benzene can prevent cell damaged, deteriorated sex disease treatment in the nerve particularly up, as A the sea Mo surname etc. disease up own obvious effect.Until the early part of , in order to avoid organ in carry on the transplant operation the front lead early oxidize of the experiment, German scientist again find the Ai ground benzene to have the effect that the organ of protection oxidizes.

This type oxidizes process, also is cause one of the aging main causes of early skin, so the scientist begins the research Ai ground benzene to be used for further the partial sex skin maintains up of effect.

The Ai ground the benzene is most the antioxidant of the new generation, by assist The plain Q10 derivatives synthesize a conversion since then, but its numerator and then more the Q10 is small , wearing skin deeply power is better, so the anti- oxidize the result nature would also more obvious.

There has been clinic reporting a manifestation currently,  in the density of comparison basis under, the Ai ground the benzene anti- oxidize of the result surmount left Xuan C, vitamin A, the vitamin E and assist Plain Q10, use the Ai ground of the medicine benzene for Alzheimer's Disease at first, also become aging skin care products of anti- now of one of the popular compositions.

As for the streets skin care products is familiar currently, also behaving the anti- been familiar with to oxidize composition more, including to have left Xuan C, vitamin A, vitamin E and assisting Plain Q10.Among them, the numerator of the left Xuan C is all vitamin C leasts of, can go deep into a skin deep, moderate to swim to leave a free radicals, but the left Xuan C is unsteady and is oxidized easily, use in the anti- the old skin care products and must notice whether change in character, and to compare with incitement, left Xuan C, the sensitivity skin usage up need to notice particularly.The vitamin AN also belongs to a more exciting antioxidant, the not appropriate usage causes to shed skin easily.

In comparison, vitamin E, assist The plain Q10 and the Ai ground benzene(Idebenone) then is more gentle, also comparing to cause an allergy not easily.

And among them, the vitamin E is a lipid-soluble vitamin, can gobble up a free radicals of causing the machine body decrepitude.As far as assist  hotlyPlain Q10 then is an important material in the human body, can moderate a free radicals, helping foreign factor of protection to hurt to what skin causes, and providing the energy that the skin metabolism needs, letting skin tight Zhi, smooth.

And more the antioxidant Ai ground of the new generation benzene, then by assist The plain Q10 derivatives synthesize a conversion since then, but its numerator and then more the Q10 is small , wearing skin deeply power is better, and its anti- oxidize result to have already been confirmed as well.

Besides, many persons think the work of"the anti- is old" just starts after being  years old.But, professional skin section doctor point out, in fact the person's skin from be born and then start experiencing the growth and"aging" process, anti- the old work wants in fact to do since the childhood.Young skin anti- the old way is easy, only needing to notice to defend to insolate and daily life.Wait for to the age to grow gradually, because the ability of the metabolism reduces, have to use to have the skin care products that the anti- oxidizes composition to make whole shortage of.

Can cause the aging reason of skin be divided into inside because of sex and outside because of sex both side.The former includes to secrete the gene that the decrease, and the metabolism deceleration causes because of the heredity gene characteristic, hormone aging, and is subjected to the aging omen that the gravitation pull of the earth influence causes;The latter includes then is changed by temperature, degree of humidity, air pollution, ozone etc. the environment factor, with smoke, sit up, the pressure is personal to cause habitually over great etc. of the free radicals increase to get, accelerating a skin of aging, and cause the super age aging cause"the light is aging" wait for.

As for skin aging performance, like this belong to inside because sex is aging, having another will produce thin crease, skin flabby etc. problem, and will have a skin to lose the structure and function characteristic;If the sunlight is aging, the above-mentioned thick thin crease produces, besides which, , will also have the skin form coarseness to fall scraps, skin to relax to increase thick, the blood vessel extend, insolate the spot and liver spot, and pore to stop bulky etc. omen, the people should notice particularly. 

 

五、Conclusion:

And the Ai ground the benzene Idebenone is one of the derivatives that few several kinds have the Coenzyme Q10 effects.Not only was had by the clinical studies confimation tightly and actually skin, face-lifting, raise to protect the water degree to reach agreement a skin color definitely isn't all.

The Ai ground benzene in addition to anti- the aging result has already approved to confirm to have fair effect through an American FDA as well outside, because Ai ground benzene can the nerve obstacle of the anti- nerve alkali, have accelerative function to the nerve conduction of the cell, can excrete the melanin of the cell quickly, can also keep fat from leading to oxidize, have protective function to the cell membrane and the grain line body.

The Ai ground the function of the benzene another as prevent the brains grain from line body to inflate to lack by reducing part the nerve cell that the guts causes breakage condition, since can promote attention, learning efficiency and memory, can also increase the ability of the vitality and cognition, promote the organ protection and defer obviously aging, and heart function.

Get one what to lift BE, the Ai ground the benzene is poisoned to lactic acid with suffer a stroke of rehabilitation also helpful, can recover the cell function, have the anti- aging result to the body cell and the skin cell, and only wipe or spread to use through the skin, all have help to the whole body cells.

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