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艾地苯.Idebenone

一、Introduction:
Idebenone
Medicine product name: The
Ai ground benzene
English:IDEBENONE TABLETS
[Nickname]:The Ya companion,
the Qian J AN oxygen Tong, Avan
Molecular formula:C19H30O5
Molecular weight:338.44
[Sex form]:
The orange
goes to an orange crystallize, the crystallinity powder or piece
form thing, have no smelly;BE dissolved in chloroform, methyl
alcohol easiest
Or have no
water ethanol, is dissolved in the acetic acid B ester easily,
difficult dissolve in B alkane, is dissolved in a water scarcely .
[The
function and use]:
Participate
the cell line grain a body metabolism, organize function to have a
protection to make to the energy metabolism and brain that lacks the
blood Qi
Use;Can
improve the metabolism that nerve inside the brain passes quality,
raise the glucose utilization of the brain, promote a brain
The ATP is
born, repressing lactic acid born lead oxygenation with fat, protect
the stability of the afferent wall cell membrane
Sex.
Being
applicable to the improvement brain blocks the linger effect,
apoplexy linger effect, brain moves the brain cirrhosis etc.
accompanies with of the motion is low to fall, emotion obstacle,
language barrier.
[Special
note]
Pregnant
woman, breast feed to expect women to use carefully
Sometimes
can appear following condition of illness:
1.allergic
sex skin Zhen.
2.have a
poor appetite, the stomach is painful, disgusting, diarrhea.
3.the spirit
nerve respond, if move much, spasm.
4.the red
cell, white cell reduce.
5.the liver
SGOT, SGPT, the ALP increases high.
6.the kidney
BUN increase high.
7.have no
power, languid, total cholesterol and glycerin three esters increase
high.
二、The
Ai ground the medical treatment of the benzene is applied:
Was in 1986
at the earliest stage, by Japanese top pharmaceutical factory
develop, afterwards the German medical treatment research team found
the Ai ground benzene Idebenone and can prevent the cell was
damaged, deteriorating sex disease treatment in the nerve
particularly up, as A the sea Mo surname etc. disease up own obvious
effect.
Through data
of the collections know, currently by many know Idebenone in the
data is a kind of to use to cure related disease with the brain of a
kind of medicine, also by know in many cultural heritage reports, it
resists oxygenation very effectively, due to it of the structure
types and CoQ10 are very alike, think is belong to CoQ10 of a kind
of, currently most Idebenones all of academic sex data is do
treatment brain related disease of part is aging or improve the
crease aspect to the skin anti- still in the research.
Pharmacology
poisonous reason:
Metabolize
for the brain, the spirit condition of illness improvement medicine,
can start the brain line grain the body breath activity, improve a
cerebral ischemia of the brain energy metabolism, the improvement
glucose utilization inside the brain, make the ATP creation inside
the brain increase, repress the brain line grain a body born lead
oxidize a fat, repress the brain line grain the body film fat over
the oxygenation with the result that of film obstacle.This article
the poisonous pair respond low, LD small rat, big rat, the big rat
Take orally half year, the dog took orally and don't see an obvious
toxicity respond for a year, have no with the result that Ji,
cancer-causing, with the result that mutate a function.
The medicine
generation dynamics:
Take orally
this article after the linger effect sufferer's rice in 6
brain Zus according to the data report, Tmax is hours, Cmax
for , remove a half- life for hours, didn't check the original
shape medicine in the urine, all in order to metabolize a thing,
urine in hours is in the excretion rate.
Adaption:
The brain
function that chronic and cerebral disease and the brain external
injury etc. cause injures.Can improve subjective condition of
illness, language, worry anxiously, suppress Yu and remember a
decrease, intelligence to descend etc. spirit behavior obstacle.
Bad
reaction:
The bad
reaction occurrence rate is or so, mainly having an allergy,
skin Zhen, disgusting, have a poor appetite, diarrhea, excitement,
suffer from insomnia, dizzy etc..See the white cell decrease, the
liver function damage accidentally.
Taboo
disease:
The special
note takes over a long period of time, notice to check GOT, GPT etc.
liver function.
三、The
Ai ground the chemistry type of the benzene:
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Name |
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Synonyms |
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Chinese Names |
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Molecular Structure |
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Molecular Formula |
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C19H30O5 |
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Molecular Weight |
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338.44 |
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CAS Registry Number |
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58186-27-9 |

四、The
Ai ground the hairdressing effect of the benzene:
The Ai
ground the benzene Idebenone belong to a type of nerve protection
benzene , From can repress the human body free radicals to assist
enzyme Q10 living creature to synthesize a conversion since then of,
is a kind of bright and orange powder.
The Ai
ground the benzene was in 1986 at the earliest stage, by Japanese
top pharmaceutical factory develop, afterwards the German medical
treatment research team found, the Ai ground the benzene can prevent
cell damaged, deteriorated sex disease treatment in the nerve
particularly up, as A the sea Mo surname etc. disease up own obvious
effect.Until the early part of , in order to avoid organ in carry on
the transplant operation the front lead early oxidize of the
experiment, German scientist again find the Ai ground benzene to
have the effect that the organ of protection oxidizes.
This type
oxidizes process, also is cause one of the aging main causes of
early skin, so the scientist begins the research Ai ground benzene
to be used for further the partial sex skin maintains up of effect.
The Ai
ground the benzene is most the antioxidant of the new generation, by
assist The plain Q10 derivatives synthesize a conversion since then,
but its numerator and then more the Q10 is small , wearing skin
deeply power is better, so the anti- oxidize the result nature would
also more obvious.
There has
been clinic reporting a manifestation currently, in the
density of comparison basis under, the Ai ground the benzene anti-
oxidize of the result surmount left Xuan C, vitamin A, the vitamin E
and assist Plain Q10, use the Ai ground of the medicine benzene for
Alzheimer's Disease at first, also become aging skin care products
of anti- now of one of the popular compositions.
As for the
streets skin care products is familiar currently, also behaving the
anti- been familiar with to oxidize composition more, including to
have left Xuan C, vitamin A, vitamin E and assisting
Plain Q10.Among them, the numerator of the
left Xuan C is all vitamin C leasts of, can go deep into a skin
deep, moderate to swim to leave a free radicals, but the left Xuan C
is unsteady and is oxidized easily, use in the anti- the old skin
care products and must notice whether change in character, and to
compare with incitement, left Xuan C, the sensitivity skin usage up
need to notice particularly.The vitamin AN also belongs to a more
exciting antioxidant, the not appropriate usage causes to shed skin
easily.
In
comparison, vitamin E, assist The plain Q10 and the Ai ground
benzene(Idebenone) then is more gentle, also comparing to cause an
allergy not easily.
And among
them, the vitamin E is a lipid-soluble vitamin, can gobble up a free
radicals of causing the machine body decrepitude.As far as assist
hotlyPlain Q10 then is an important material in the human body, can
moderate a free radicals, helping foreign factor of protection to
hurt to what skin causes, and providing the energy that the skin
metabolism needs, letting skin tight Zhi, smooth.
And more the
antioxidant Ai ground of the new generation benzene, then by assist
The plain Q10 derivatives synthesize a conversion since then, but
its numerator and then more the Q10 is small , wearing skin deeply
power is better, and its anti- oxidize result to have already been
confirmed as well.
Besides,
many persons think the work of"the anti- is old" just starts after
being years old.But, professional skin section doctor point
out, in fact the person's skin from be born and then start
experiencing the growth and"aging" process, anti- the old work wants
in fact to do since the childhood.Young skin anti- the old way is
easy, only needing to notice to defend to insolate and daily
life.Wait for to the age to grow gradually, because the ability of
the metabolism reduces, have to use to have the skin care products
that the anti- oxidizes composition to make whole shortage of.
Can cause
the aging reason of skin be divided into inside because of sex and
outside because of sex both side.The former includes to secrete the
gene that the decrease, and the metabolism deceleration causes
because of the heredity gene characteristic, hormone aging, and is
subjected to the aging omen that the gravitation pull of the earth
influence causes;The latter includes then is changed by temperature,
degree of humidity, air pollution, ozone etc. the environment
factor, with smoke, sit up, the pressure is personal to cause
habitually over great etc. of the free radicals increase to get,
accelerating a skin of aging, and cause the super age aging
cause"the light is aging" wait for.
As for skin
aging performance, like this belong to inside because sex is aging,
having another will produce thin crease, skin flabby etc. problem,
and will have a skin to lose the structure and function
characteristic;If the sunlight is aging, the above-mentioned thick
thin crease produces, besides which, , will also have the skin form
coarseness to fall scraps, skin to relax to increase thick, the
blood vessel extend, insolate the spot and liver spot, and pore to
stop bulky etc. omen, the people should notice particularly.
五、Conclusion:
And the Ai
ground the benzene Idebenone is one of the derivatives that few
several kinds have the Coenzyme Q10 effects.Not only was had by the
clinical studies confimation tightly and actually skin,
face-lifting, raise to protect the water degree to reach agreement a
skin color definitely isn't all.
The Ai
ground benzene in addition to anti- the aging result has already
approved to confirm to have fair effect through an American FDA as
well outside, because Ai ground benzene can the nerve obstacle of
the anti- nerve alkali, have accelerative function to the nerve
conduction of the cell, can excrete the melanin of the cell quickly,
can also keep fat from leading to oxidize, have protective function
to the cell membrane and the grain line body.
The Ai
ground the function of the benzene another as prevent the brains
grain from line body to inflate to lack by reducing part the nerve
cell that the guts causes breakage condition, since can promote
attention, learning efficiency and memory, can also increase the
ability of the vitality and cognition, promote the organ protection
and defer obviously aging, and heart function.
Get one what
to lift BE, the Ai ground the benzene is poisoned to lactic acid
with suffer a stroke of rehabilitation also helpful, can recover the
cell function, have the anti- aging result to the body cell and the
skin cell, and only wipe or spread to use through the skin, all have
help to the whole body cells. |
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